DOI: 10.2217/fon-2022-0930 ISSN:
Effect of preoperative peripheral blood platelet volume index on prognosis in patients with invasive breast cancer
Kai Huang, Suosu Wei, Zhen Huang, Yujie Xie, Chunyu Wei, Jinan Xu, Lingguang Dong, Quanqing Zou, Jianrong Yang- Cancer Research
- Oncology
- General Medicine
Aim: This study was designed to investigate the prognostic value of the platelet volume index in patients with invasive breast cancer (IBC). Methods: A total of 524 patients with IBC were enrolled in this study, with a median follow-up time of 6.76 years. The relationship between platelet volume indices and breast cancer prognosis was analyzed. Results: There is a strong correlation between a higher platelet distribution width-to-platelet count ratio (PDW/P) and poorer disease-free survival (DFS) in patients with IBC. The DFS rate was significantly lower among individuals with elevated PDW/P ratios compared with those with lower ratios. Conclusion: The PDW/P ratio is an independent risk factor for predicting DFS in patients with IBC.