Effect of ciprofol on swallowing function in patients undergoing painless gastrointestinal endoscopy
Jinsong Liao, Shun Lv, Xiong Wang, Yu Ye, Qiuyu Zhang, Lin Zeng, Shuhua Dong- General Medicine
Background:
Gastroscopy is one of the most commonly used diagnostic modalities for upper gastrointestinal disorders. This study compared the effect of ciprofol and propofol on swallowing function during painless gastroenteroscopy.
Methods:
This was a single-center, placebo-controlled randomized trial. Three hundred sixty-eight patients undergoing painless gastroscopy were included in this study and randomly divided into 2 groups: the propofol group (PRO group, n = 183) and the ciprofol group (CIP group, n = 185). Sufentanil, ciprofol, and propofol are used to anesthetize the patients, and the effects of different solutions on these patients are compared and analyzed. The patient’s general condition, vocal cord adduction reflex, dysphagia severity score, penetration and aspiration scale score, vital signs at different times, complications, recovery time (minutes), residence time in the resuscitation room (minutes), and adverse reactions were recorded.
Results:
During the examination, the incidence of severe swallowing dysfunction in CIP group was lower than that in PRO group (
Conclusion:
Compared with propofol, ciprofol has less inhibition on swallowing function, less impact on hemodynamics, less respiratory depression, and less injection pain, which is more suitable for painless gastroscopy.