DOI: 10.1039/d3qo00951c ISSN:
Direct enantioselective α-alkylation of secondary acyclic amines with ketones by combining photocatalysis and lipase catalytic promiscuity
Chao-Jiu Long, Hong-Ping Pu, Yan-Hong He, Zhi Guan- Organic Chemistry
Described is a method for directly achieving enantioselective α-alkylation of secondary acyclic amines with ketones through the combination of photocatalysis and the catalytic promiscuity of lipase.