DOI: 10.1039/d3sc03258b ISSN:
C(sp2)–H cyclobutylation of hydroxyarenes enabled by silver-π-acid catalysis: diastereocontrolled synthesis of 1,3-difunctionalized cyclobutanes
Lei Tang, Qi-Nan Huang, Feng Wu, Yuanjiu Xiao, Jin-Lan Zhou, Tong-Tong Xu, Wen-Biao Wu, Shuanglin Qu, Jian-Jun Feng- General Chemistry
A carbophilic silver Lewis acid catalyzes polar strain-release ring-opening of BCBs with hydroxyarenes to afford 1,1,3-trisubstituted cyclobutanes in high yields and excellent chemo- and diastereoselectivity.