DOI: 10.1039/d3qo00871a ISSN:
Copper-catalyzed asymmetric propargylation of imines enabled by a biphenol-based phosphoramidite ligand
Qi-Qi Yan, Cheng-Kai Ruan, Yu-Qin Deng, Yu-Chuan Pu, Wen-Dao Chu, Cheng-Yu He, Quan-Zhong Liu- Organic Chemistry
Cu-catalyzed asymmetric propargylation of acyclic imines with electron-neutral protecting groups was established, providing the corresponding homopropargyl amines in excellent yields and high enantioselectivities.